Richardson RT, Sivashanmugam P, Hall SH, Hamil KG, Moore PA, Ruben SM, et al.
Gene. 2001 May 30;270(1–2):93–102. PMID:11404006
Yenugu S, Richardson RT, Sivashanmugam P, Wang Z, O'Rand MG, French FS, Hall SH.
Biol Reprod. 2004 Nov;71(5):1484-90. Epub 2004 Jun 30. PMID:15229136
Reversible immunocontraception in male monkeys immunized with eppin.
O'Rand MG, Widgren EE, Sivashanmugam P, Richardson RT, Hall SH, French FS, VandeVoort CA, Ramachandra SG, Ramesh V, Jagannadha Rao A.
Science. 2004 Nov 12;306(5699):1189-90. PMID:15539605
Association of eppin with semenogelin on human spermatozoa.
Wang Z, Widgren EE, Sivashanmugam P, O'Rand MG, Richardson RT.
Biol Reprod. 2005 May;72(5):1064-70. Epub 2004 Dec 8. PMID:15590901
Characterization of an eppin protein complex from human semen and spermatozoa.
Wang Z, Widgren EE, Richardson RT, O'Rand MG.
Biol Reprod. 2007 Sep;77(3):476-84. Epub 2007 Jun 13. PMID:17567961
O'Rand MG, Widgren EE, Beyler S, Richardson RT.
Biol Reprod. 2009 Feb;80(2):279-85. Epub 2008 Oct 22. PMID: 18945989
Analysis of recombinant human semenogelin as an inhibitor of human sperm motility.
Mitra A, Richardson RT, O'Rand MG.
Biol Reprod. 2010 Mar;82(3):489-96. Epub 2009 Nov 4.PMID: 19889947
O’Rand MG, Widgren EE, Hamil KG, Silva EJ, Richardson RT. J Androl. 2011 Dec;32(6):698–704. Epub 2011 Mar 25. Review. PMID: 21441428
Loss of calcium in human spermatozoa via EPPIN, the semenogelin receptor.
O'Rand MG, Widgren EE Biol Reprod. 2012 Feb 29;86(2):55. doi: 10.1095/biolreprod.111.094227. Print 2012 Feb. PMID: 22075473
Characterization of EPPIN's semenogelin I binding site: a contraceptive drug target.
Silva EJR, Hamil KG, Richardson RT, O’Rand MG.
Biol Reprod. 2012 Sep;87(3):56, Print 2012 Sep. PMID:22699487
Silva EJR, Hamil KG, O’Rand MG.. PloS One. 2013;8(12):e82014. eCollection 2013. PMID:24312623.
Non-hormonal male contraception: A review and development of an Eppin based contraceptive.
O’Rand MG, Silva EJR, Hamil KG.
Pharmacol Ther. 2016 Jan;157:105–11. PMID: 26593445
Inhibition of sperm motility in male macaques with EP055, a potential non-hormonal male contraceptive
Michael G. O’Rand, Katherine G. Hamil, Tiffany Adevai, Mary Zelinski
PLOS One April 19 2018
PMCID: PMC5908160
Interactions of the male
contraceptive target EPPIN
with semenogelin‑1 and small
organic ligands
Antoniel A. S. Gomes, Natália C. M. Santos, Leonardo R. Rosa, Rafael J. Borges
Scientific Reports | (2023) 13:14382 https://doi.org/10.1038/s41598-023-41365-1
Male Contraception Initiative works with researchers across the globe to make male contraceptive options a reality.
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